Mediator Phosphorylation Prevents Stress Response Transcription During Non-stress Conditions
نویسندگان
چکیده
منابع مشابه
Mediator phosphorylation prevents stress response transcription during non-stress conditions.
The multiprotein complex Mediator is a coactivator of RNA polymerase (Pol) II transcription that is required for the regulated expression of protein-coding genes. Mediator serves as an end point of signaling pathways and regulates Pol II transcription, but the mechanisms it uses are not well understood. Here, we used mass spectrometry and dynamic transcriptome analysis to investigate a function...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m112.430140